Biological Influences on Obesity.
From: Department of Pediatrics, University of California Davis Medical Center, Sacramento, California, USA. naschonfeldwarden@ucdavis.edu
Pediatric clinics of North America
- Publish Date: Aug 2001
- ISSN: 0031-3955
- Volume: 48
- Issue: 4
- Pages: 879-91
- Medium: Print
- Language: English
- Citation (JAMA): Warden N A, Warden C H, et al. Biological Influences on Obesity.. Pediatr. Clin. North Am. Aug 2001;48:879-91
Abstract
Severely obese children are even more likely to have mutations in obesity genes than are severely obese adults. Thus, investigators searching for obesity genes commonly focus on children, with the result that many human obesity genes were first identified in studies of children. Although the development of obesity depends on living in an obesity-promoting environment, it also is influenced strongly by individual genetic composition. Thus, the discovery of new obesity genes provides new opportunities to identify causes of severe obesity. Finally, identification of individual causes of obesity may, in the future, provide for a safe, effective, and individualized treatment recommendation for each obese person.
Mesh Headings (Keywords): Animals, Disease Models, Animal, Genetic Predisposition to Disease, Humans, Leptin, Mice, Models, Genetic, Obesity, Oligonucleotide Array Sequence Analysis, Pro-Opiomelanocortin, Receptors, Corticotropin, Receptors, Melanocortin
Check for Full Text / PubMed Unique Identifier (PMID): 11494641
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