Bleeding Disorder As the First Symptom of Biliary Atresia.
From: Department of Pediatric Surgery, Pathology and First Surgery, Hokkaido University School of Medicine, Sapporo, Japan. okadata@med.hokudai.ac.jp
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie
- Publish Date: Aug 2005
- ISSN: 0939-7248
- Volume: 15
- Issue: 4
- Pages: 295-9
- Medium: Print
- Language: English
- Citation (JAMA): Okada T, Sasaki F, Itoh T, et al. Bleeding Disorder As the First Symptom of Biliary Atresia.. Aug 2005;15:295-9
Abstract
Biliary atresia (BA) is occasionally diagnosed in infants whose first symptom is a bleeding disorder, such as intracranial bleeding, nasal bleeding or gastrointestinal bleeding. The authors describe 3 cases in which a bleeding disorder was the first symptom of BA. The presenting symptom was intracranial bleeding in a male on day 55 after birth, nasal bleeding in a female at 65 days, and gastrointestinal bleeding in a female at 25 days. Coagulation studies revealed a vitamin K deficiency in all patients. After the administration of vitamin K, the results of coagulation tests normalized and the bleeding tendency of the infants ceased. Subsequently, BA was suspected to be the cause of these bleeding disorders based on imaging findings. BA should therefore be considered in all infants with sudden onset of a tendency to bleed.
Mesh Headings (Keywords): Biliary Atresia, Cholangiography, Female, Hematoma, Subdural, Humans, Infant, Liver Transplantation, Male, Subarachnoid Hemorrhage, Vitamin K, Vitamin K Deficiency
Check for Full Text / PubMed Unique Identifier (PMID): 16163599
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