Total and Specific Fluid Consumption As Determinants of Bladder Cancer Risk.
From: Respiratory and Environmental Health Research Unit, Institut Municipal d’Investigació Mèdica (IMIM), Barcelona, Spain. cvillanueva@imim.es
International journal of cancer. Journal international du cancer
- Publish Date: Apr 2006
- ISSN: 0020-7136
- Volume: 118
- Issue: 8
- Pages: 2040-7
- Medium: Print
- Language: English
- Citation (JAMA): Villanueva Cristina M, Cantor Kenneth P, King Will D, et al. Total and Specific Fluid Consumption As Determinants of Bladder Cancer Risk.. Int. J. Cancer Apr 2006;118:2040-7
Abstract
We pooled the data from 6 case-control studies of bladder cancer with detailed information on fluid intake and water pollutants, particularly trihalomethanes (THM), and evaluated the bladder cancer risk associated with total and specific fluid consumption. The analysis included 2,729 cases and 5,150 controls. Odds ratios (OR) and 95% confidence intervals (CI) for fluid consumption were adjusted for age, gender, study, smoking status, occupation and education. Total fluid intake was associated with an increased risk of bladder cancer in men. The adjusted OR for 1 l/day increase in intake was 1.08, (95% CI 1.03-1.14, p-value for linear trend <0.001), while no trend was observed in women (OR=1.04, 0.94-1.15; p-value=0.7). OR was 1.33 (1.12-1.58) for men in the highest category of intake (>3.5 l/day) as compared to those in the lowest (
Mesh Headings (Keywords): Age Factors, Aged, Carcinogens, Case-Control Studies, Drinking Behavior, Female, Humans, Male, Middle Aged, Odds Ratio, Risk Factors, Sex Factors, Urinary Bladder Neoplasms, Water Supply
Check for Full Text / PubMed Unique Identifier (PMID): 16284957
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