Hvrbase++: a Phylogenetic Database for Primate Species.
From: Heinrich-Heine-University Duesseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany.
Nucleic acids research
- Publish Date: Jan 2006
- ISSN: 1362-4962
- Volume: 34
- Issue: Database issue
- Pages: D700-4
- Medium: Internet
- Language: English
- Citation (JAMA): Kohl Jochen, Paulsen Ingo, Laubach Thomas, et al. Hvrbase++: a Phylogenetic Database for Primate Species.. Nucleic Acids Res. Jan 2006;34:D700-4
Abstract
HvrBase++ is the improved and extended version of HvrBase. Extensions are made by adding more population-based sequence samples from all primates including humans. The current collection comprises 13,873 hypervariable region I (HVRI) sequences and 4940 hypervariable region II (HVRII) sequences. In addition, we included 1376 complete mitochondrial genomes, 205 sequences from X-chromosomal loci and 202 sequences from autosomal chromosomes 1, 8, 11 and 16. In order to reduce the introduction of erroneous data into HvrBase++, we have developed a procedure that monitors GenBank for new versions of the current data in HvrBase++ and automatically updates the collection if necessary. For the stored sequences, supplementary information such as geographic origin, population affiliation and language of the sequence donor can be retrieved. HvrBase++ is Oracle based and easily accessible by a web interface (http://www.hvrbase.org). As a new key feature, HvrBase++ provides an interactive graphical tool to easily access data from dynamically created geographical maps.
Mesh Headings (Keywords): Animals, Chromosomes, Mammalian, Computer Graphics, DNA, Mitochondrial, Databases, Nucleic Acid, Genetics, Population, Humans, Internet, Phylogeny, Primates, Sequence Analysis, DNA, User-Computer Interface
Check for Full Text / PubMed Unique Identifier (PMID): 16381963
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