Cryoglobulinemia in Chronic Hepatitis C Virus Infection. About 76 Cases
From: Service de Gastro entérologie A. Hopital la Rabta. Túnis, Tunisie.
La Tunisie médicale
- Publish Date: Nov 2005
- ISSN: 0041-4131
- Volume: 83
- Issue: 11
- Pages: 664-8
- Medium: Print
- Language:
- Citation (JAMA): Monia Fekih, Lamia Bouallegue, Jalel Boubaker, et al. Cryoglobulinemia in Chronic Hepatitis C Virus Infection. About 76 Cases. Nov 2005;83:664-8
Abstract
Cryolobulines are immunoglobulins that persist in the serum, precipitate with cold temperature and resolubilize when rewarmed. There are 3 types of cryoglobulinemia. Type II and III define mixed cryoglobulinemia. 40% approximately of patients with chronic hepatitis C virus (HCV) infection had cryoglobulinemia. OBJECTIVE: To evaluate the frequency of cryoglobulinemia in a chronic hepatitis virus (CHV) infection group and determine the characteristics of positive cryoglobulinemia patients. RESULTS: 76 patients were included. There were 53 women an 23 men. The mean age was 59.45 years. Mixed cryoglobulinemia was detected in 65 patients (85.5 %). Cirrhosis, old age and the long duration of CHV infection were the 3 factors associated with cryoglobulinemia positivity. CONCLUSION: Mixed cryoglobulinemia is a frequent manifestation during chronic hepatitis C infection virsus especially in patients with cirrhosis.
Mesh Headings (Keywords): Age Factors, Cryoglobulinemia, Cryoglobulins, Female, Hepatitis C, Chronic, Humans, Immunoglobulin A, Immunoglobulin G, Immunoglobulin M, Liver Cirrhosis, Male, Middle Aged, Time Factors
Check for Full Text / PubMed Unique Identifier (PMID): 16422362
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