Habitual Green Tea Consumption and Risk of an Aneurysmal Rupture Subarachnoid Hemorrhage: a Case-control Study in Nagoya, Japan.
From: Department of Epidemiology, Aichi Prefectural College of Nursing and Health, Nagoya, Japan. okamoto@aichi-nurs.ac.jp
European journal of epidemiology
- Publish Date: 2006
- ISSN: 0393-2990
- Volume: 21
- Issue: 5
- Pages: 367-71
- Medium: Print
- Language: English
- Citation (JAMA): Okamoto Kazushi, et al. Habitual Green Tea Consumption and Risk of an Aneurysmal Rupture Subarachnoid Hemorrhage: a Case-control Study in Nagoya, Japan.. Eur. J. Epidemiol. 2006;21:367-71
Abstract
BACKGROUND: Green tea, a popular beverage in Japan, contains many polyphenolic antioxidants, which might prevent cardiovascular disease. This study is designed to determine whether the consumption of green tea is associated with a reduced risk for subarachnoid hemorrhage (SAH) using a case-control study. METHODS: Incident SAH cases (n=201) were identified and individually matched by age (+/-2 years) and gender to hospital (n=201) and community controls (n=201) from April 1992 to March 1997. Habitual regular tea consumption was assessed with a structured questionnaire. Conditional logistic regression models were used to compute odds ratios adjusted for smoking, history of hypertension, and educational levels. RESULTS: The proportion of the consumption of one time or more of tea per day was higher in controls (70.9%) than in SAH patients (60.3%). Multivariate analyses showed that green tea consumption was inversely associated with SAH risk. Subjects consuming <1, and >or=1 time per day had adjusted ORs of 0.74 (CI: 0.34-1.58), and 0.56 (CI: 0.32-0.98) in comparison with non daily green tea drinkers, respectively (p-trend <0.001). CONCLUSION: In a case-control study in Japan, we found that habitual green tea consumption may be strongly associated with a reduced risk for SAH. Our findings will be useful in targeting individuals and populations for the primary prevention of SAH.
Mesh Headings (Keywords): Adult, Aged, Aneurysm, Ruptured, Case-Control Studies, Female, Humans, Japan, Male, Middle Aged, Odds Ratio, Risk Factors, Subarachnoid Hemorrhage, Tea
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