Electrochemical Snps Detection Using an Abasic Site-containing Dna on a Gold Electrode.
From: Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan.
Chemical communications (Cambridge, England)
- Publish Date: Jun 2006
- ISSN: 1359-7345
- Volume:
- Issue: 22
- Pages: 2376-8
- Medium: Print
- Language: English
- Citation (JAMA): Morita Kotaro, Sankaran N B, Huang Weimin, et al. Electrochemical Snps Detection Using an Abasic Site-containing Dna on a Gold Electrode.. Chem. Commun. (Camb.) Jun 2006;:2376-8
Abstract
An abasic site-containing DNA combined with lumiflavin allows amperometric determination of single nucleotide polymorphism through hydrogen bond-mediated nucleobase recognition in water by using abasic sites as a molecular recognition field.
Mesh Headings (Keywords): Base Pairing, Binding Sites, DNA, Electrochemistry, Electrodes, Flavins, Gold, Hydrogen Bonding, Ligands, Polymorphism, Single Nucleotide, Surface Properties, Water
Check for Full Text / PubMed Unique Identifier (PMID): 16733585
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