'migraine and a Hole in the Heart': Causal Relationship Between Migraine and Patent Foramen Ovale Not Established
From: Leids Universitair Medisch Centrum, Albinusdreef 2, 2333 ZA Leiden.
Nederlands tijdschrift voor geneeskunde
- Publish Date: May 2006
- ISSN: 0028-2162
- Volume: 150
- Issue: 19
- Pages: 1050-2
- Medium: Print
- Language:
- Citation (JAMA): Terwindt G M, Haan J, Bax J J, et al. 'migraine and a Hole in the Heart': Causal Relationship Between Migraine and Patent Foramen Ovale Not Established. May 2006;150:1050-2
Abstract
The relationship between patent foramen ovale (PFO) and migraine is controversial. A common genetic background seems possible, but there is no evidence for a causal relationship. Despite the lack of evidence, PFO closure is recommended in many countries as a remedy for migraine. At present, PFO closure for migraine should only be carried out under strictly controlled clinical trial conditions.
Mesh Headings (Keywords): Genetic Predisposition to Disease, Heart Septal Defects, Atrial, Humans, Migraine Disorders, Risk Factors
Check for Full Text / PubMed Unique Identifier (PMID): 16733978
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