Infrared Micro-spectroscopic Studies of Epithelial Cells.
From: Department of Chemistry and Biochemistry, City University of New York, Hunter College, New York, NY 10021, USA. m.romeo@neu.edu
Biochimica et biophysica acta
- Publish Date: Jul 2006
- ISSN: 0006-3002
- Volume: 1758
- Issue: 7
- Pages: 915-22
- Medium: Print
- Language: English
- Citation (JAMA): Romeo Melissa, Mohlenhoff Brian, Jennings Michael, et al. Infrared Micro-spectroscopic Studies of Epithelial Cells.. Biochim. Biophys. Acta Jul 2006;1758:915-22
Abstract
We report results from a study of human and canine mucosal cells, investigated by infrared micro-spectroscopy, and analyzed by methods of multivariate statistics. We demonstrate that the infrared spectra of individual cells are sensitive to the stage of maturation, and that a distinction between healthy and diseased cells will be possible. Since this report is written for an audience not familiar with infrared micro-spectroscopy, a short introduction into this field is presented along with a summary of principal component analysis.
Mesh Headings (Keywords): Animals, Cervix Uteri, Dogs, Epithelial Cells, Female, Humans, Microscopy, Mouth Mucosa, Spectrophotometry, Infrared
Check for Full Text / PubMed Unique Identifier (PMID): 16797481
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