The Vasoactive Intestinal Peptide Receptor Turnover in Pulmonary Arteries Indicates an Important Role for Vip in the Rat Lung Circulation.
From: Medical University Vienna, KIM-1, Institute of Cancer Research, Borschkegasse 8a, A-1090 Wien, Austria.
Annals of the New York Academy of Sciences
- Publish Date: Jul 2006
- ISSN: 0077-8923
- Volume: 1070
- Issue:
- Pages: 481-3
- Medium: Print
- Language: English
- Citation (JAMA): Petkov Ventzislav, Gentscheva Temenuschka, Schamberger Chantal, et al. The Vasoactive Intestinal Peptide Receptor Turnover in Pulmonary Arteries Indicates an Important Role for Vip in the Rat Lung Circulation.. Ann. N. Y. Acad. Sci. Jul 2006;1070:481-3
Abstract
Vasoactive intestinal peptide (VIP) is a potent vasorelaxing peptide that plays a role in lung physiology and possibly in pulmonary hypertension. We investigated the turnover of the VIP receptors on rat pulmonary arteries ex vivo. There was evidence for a fast receptor turnover in pulmonary arteries, which underlines the important role of VIP for the regulation of pulmonary circulation and pulmonary pathology.
Mesh Headings (Keywords): Acetylcholine, Animals, Male, Pulmonary Artery, Pulmonary Circulation, Rats, Rats, Sprague-Dawley, Receptors, Vasoactive Intestinal Peptide, Vasoactive Intestinal Peptide
Check for Full Text / PubMed Unique Identifier (PMID): 16888213
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