Microbial Inhibitors of Lysozyme
Zhurnal mikrobiologii, epidemiologii, i immunobiologii
- Publish Date:
- ISSN: 0372-9311
- Volume:
- Issue: 4
- Pages: 8-13
- Medium: Print
- Language: Russian
- Citation (JAMA): Bukharin O V, Valyshev A V, et al. Microbial Inhibitors of Lysozyme. Zh. Mikrobiol. Epidemiol. Immunobiol. ;:8-13
Abstract
Lysozyme is one of the most important factors of innate immunity, possessing anti-microbial action against a wide range of microorganisms due to cationic nature of protein and, in a lesser degree, due to muramidase activity. In the process of evolution, different mechanisms of lysozyme inhibition, defined as anti-lysozyme activity (ALA), were formed in microorganisms. The usage of the delayed antagonism principle allowed to reveal anti-lysozyme sign in microorganisms of different phylogenetic groups. In the review, data on the occurrence and level of anti-lysozyme activity in pathogens and representatives of normal microflora were presented; findings on nature and genetic determinants of lysozyme inhibitors are given. questions on drug regulation of ALA of the causative agents in infectious diseases and dysbiotic conditions are discussed.
Mesh Headings (Keywords): Animals, Bacteria, Bacterial Infections, Bacterial Proteins, Bacteriological Techniques, Culture Media, Defensins, Evolution, Fungi, Humans, Hydrogen-Ion Concentration, Immunity, Natural, Muramidase, Probiotics, Temperature
Check for Full Text / PubMed Unique Identifier (PMID): 16941860
This abstract is part of PubMed, a service of the U.S. National Library of Medicine. PubMed includes more than 17 million citations from MEDLINE and other life science journals for biomedical articles. See Copyright and Disclaimers.
Linked medical terms appearing on this page are added by Healia to help readers find more information and are not part of the original PubMed document.
The data herein was last updated on July 8th, 2008 and may not reflect the most current and accurate data available from NLM.