Carbohydrate Nutrition, Glycaemic Load, and Plasma Lipids: the Insulin Resistance Atherosclerosis Study.
From: Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, 800 Sumter Street, Columbia, SC 29208, USA. liese@sc.edu
European heart journal
- Publish Date: Jan 2007
- ISSN: 0195-668X
- Volume: 28
- Issue: 1
- Pages: 80-7
- Medium: Print
- Language: English
- Citation (JAMA): Liese Angela D, Gilliard Theodosha, Schulz Mandy, et al. Carbohydrate Nutrition, Glycaemic Load, and Plasma Lipids: the Insulin Resistance Atherosclerosis Study.. Eur. Heart J. Jan 2007;28:80-7
Abstract
AIMS: We evaluated the relationship of carbohydrate nutrition and selected food groups with lipids using data from the Insulin Resistance Atherosclerosis Study (IRAS Exam I, 1992-1994). METHODS AND RESULTS: A total of 1026 middle-aged adults with normal or impaired glucose tolerance had complete data on fasting lipids and usual dietary intake from an interviewer-administered, validated food frequency questionnaire. Published glycaemic index (GI) values were assigned to food items and average dietary GI and glycaemic load (GL) were calculated per participant. Intake of carbohydrates differed by gender, men consuming more absolute digestible carbohydrates with higher GI and GL than women. In multivariate models adjusting for energy intake, in men, GL and carbohydrates were associated positively with total and LDL cholesterol, and inversely with HDL. In women, associations were limited to triglycerides. We estimated that a 100 g higher intake in GL or carbohydrates was associated with a 7-8 mg/dL higher total or LDL cholesterol level in men, and a 13-17 mg/dL higher triglyceride level in women. In the combined sample, GL and carbohydrates were consistently associated with all lipid levels and GI was inversely associated with HDL cholesterol. CONCLUSION: Our findings underscore the importance of carbohydrate nutrition for plasma lipids.
Mesh Headings (Keywords): Adult, Aged, Atherosclerosis, Blood Glucose, Diabetes Mellitus, Type 2, Dietary Carbohydrates, Humans, Insulin Resistance, Lipids, Middle Aged
Check for Full Text / PubMed Unique Identifier (PMID): 17132647
This abstract is part of PubMed, a service of the U.S. National Library of Medicine. PubMed includes more than 17 million citations from MEDLINE and other life science journals for biomedical articles. See Copyright and Disclaimers.
Linked medical terms appearing on this page are added by Healia to help readers find more information and are not part of the original PubMed document.
The data herein was last updated on July 8th, 2008 and may not reflect the most current and accurate data available from NLM.