Is the Metabolic Syndrome an Independent Risk Factor for Erectile Dysfunction?
From: Department of Urology and Andrology, Donauspital, Vienna, Austria.
The Journal of urology
- Publish Date: Feb 2007
- ISSN: 0022-5347
- Volume: 177
- Issue: 2
- Pages: 651-4
- Medium: Print
- Language: English
- Citation (JAMA): Heidler Stefan, Temml Christian, Broessner Clemens, et al. Is the Metabolic Syndrome an Independent Risk Factor for Erectile Dysfunction?. J. Urol. Feb 2007;177:651-4
Abstract
PURPOSE: We determined the role of the metabolic syndrome as an independent risk factor for erectile dysfunction. MATERIALS AND METHODS: Men participating in a health screening project completed the International Index of Erectile Function-5. The metabolic syndrome was defined according to the 2005 International Diabetes Federation consensus definition. Multiple linear regression, ANOVA and chi-square tests were used to investigate the impact of the metabolic syndrome on erectile dysfunction. RESULTS: A total of 2,371 men with a mean age of 46.1 years (SD 9.9, range 30 to 69) were analyzed. Of the men 33.4% (652) had no erectile dysfunction (International Index of Erectile Function-5 score 22 to 25), 59.7% (1,166) had mild erectile dysfunction (International Index of Erectile Function-5 score 17 to 21) and 6.9% (134) had moderate to severe erectile dysfunction (International Index of Erectile Function-5 score 5 to 16). The metabolic syndrome was present in 33.8% (794). In a multiple linear regression analysis an increased waist-to-hip ratio (p = 0.01) and metabolic syndrome (p = 0.01) turned out to be independently associated with a decreased International Index of Erectile Function-5 score. When stratified according to age, the metabolic syndrome was correlated to erectile dysfunction only in men 50 years old or older with an increase of severe erectile dysfunction by 48% (p = 0.01). CONCLUSIONS: The metabolic syndrome and an increased waist-to-hip ratio are independently associated with a decreased International Index of Erectile Function-5 score. The metabolic syndrome in men older than 50 years is significantly associated with a higher proportion of moderate to severe erectile dysfunction.
Mesh Headings (Keywords): Adult, Aged, Cross-Sectional Studies, Erectile Dysfunction, Humans, Male, Metabolic Syndrome X, Middle Aged, Risk Factors
Check for Full Text / PubMed Unique Identifier (PMID): 17222651
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