Association of Ambulatory Blood Pressure with Ischemic Brain Injury.
From: Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. gschwartz@mayo.edu
Hypertension
- Publish Date: Jun 2007
- ISSN: 1524-4563
- Volume: 49
- Issue: 6
- Pages: 1228-34
- Medium: Internet
- Language: English
- Citation (JAMA): Schwartz Gary L, Bailey Kent R, Mosley Thomas, et al. Association of Ambulatory Blood Pressure with Ischemic Brain Injury.. Hypertension Jun 2007;49:1228-34
Abstract
Cerebral white matter hyperintensities on brain MRI (leukoaraiosis) are associated with increased risk of stroke and dementia. To assess the relationships of blood pressure level and circadian pattern with leukoaraiosis, we obtained 24-hour ambulatory blood pressure recordings and brain magnetic resonance images in 343 white and 267 black adults who were members of sibships that had >or=2 siblings with essential hypertension. In multiple linear regression models, factors associated with greater leukoaraiosis in both racial groups included age (P
Mesh Headings (Keywords): African Continental Ancestry Group, Aged, Blood Pressure, Blood Pressure Monitoring, Ambulatory, Brain Ischemia, Circadian Rhythm, Cross-Sectional Studies, European Continental Ancestry Group, Female, Homocysteine, Humans, Leukoaraiosis, Linear Models, Magnetic Resonance Imaging, Male, Middle Aged, Sleep
Check for Full Text / PubMed Unique Identifier (PMID): 17404188
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