Turning Back the Clock on Neurodegeneration.
From: Department of Physiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53719, USA.
Cell
- Publish Date: Jun 2007
- ISSN: 0092-8674
- Volume: 129
- Issue: 5
- Pages: 851-3
- Medium: Print
- Language: English
- Citation (JAMA): Mangan Kile P, Levenson Jonathan M, et al. Turning Back the Clock on Neurodegeneration.. Cell Jun 2007;129:851-3
Abstract
Does neuronal loss associated with dementia necessarily impair the ability to learn new information and recall old memories? In a recent report in Nature, Fischer et al. (2007) show that the ability to learn and remember can be reestablished in a mouse model of dementia through either environmental enrichment or chronic treatment with an inhibitor of histone deacetylase.
Mesh Headings (Keywords): Animals, Dementia, Disease Models, Animal, Enzyme Inhibitors, Histone Deacetylases, Learning, Memory, Mice, Nerve Degeneration
Check for Full Text / PubMed Unique Identifier (PMID): 17540162
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