Composition, Irregular Terpenoids, Chemical Variability and Antibacterial Activity of the Essential Oil from Santolina Corsica Jordan Et Fourr.
From: Université de Corse, UMR CNRS 6134 SPE, Equipe Chimie et Biomasse, Route des Sanguinaires, 20000 Ajaccio, France.
Phytochemistry
- Publish Date: Jun 2007
- ISSN: 0031-9422
- Volume: 68
- Issue: 12
- Pages: 1698-705
- Medium: Print
- Language: English
- Citation (JAMA): Liu Kai, Rossi Paul-Georges, Ferrari Bernard, et al. Composition, Irregular Terpenoids, Chemical Variability and Antibacterial Activity of the Essential Oil from Santolina Corsica Jordan Et Fourr.. Phytochemistry Jun 2007;68:1698-705
Abstract
A detailed analysis of Santolina corsica essential oil was carried out by combination of GC (RI), GC-MS and 13C NMR spectroscopy. After fractionation by column chromatography, 50 components were identified, accounting for 88.2% of the total amount of the oil. The chemical composition was dominated by monoterpene hydrocarbons, myrcene (34.6%), santolina triene (13.5%) and beta-phellandrene (11.7%). Beside the main compounds, we noted the occurrence of irregular mono and sesquiterpenes belonging to five families: santolinane, artemisane, chrysanthemane, lavandulane and sesquilavandulane. Three compounds, lyratyl butyrate, isolyratone and epi-isolyratol were isolated and their structure elucidated by 2D NMR. Antibacterial activity was tested against six bacteria strains. The essential oil was effective against Staphylococcus aureus and C. jejuni. Lyratol was identified as main responsive of the antibacterial activity. The content of lyratol was measured in 33 oil samples isolated from individual plants.
Mesh Headings (Keywords): Anti-Bacterial Agents, Asteraceae, Bacteria, Gas Chromatography-Mass Spectrometry, Microbial Sensitivity Tests, Nuclear Magnetic Resonance, Biomolecular, Oils, Volatile, Terpenes
Check for Full Text / PubMed Unique Identifier (PMID): 17544463
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