Neurite Outgrowth: a Flick of the Wrist.
From: Department of Cell Biology and Institute for Childhood and Neglected Diseases, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Current biology : CB
- Publish Date: Aug 2007
- ISSN: 0960-9822
- Volume: 17
- Issue: 15
- Pages: R611-4
- Medium: Print
- Language: English
- Citation (JAMA): Dehmelt Leif, Halpain Shelley, et al. Neurite Outgrowth: a Flick of the Wrist.. Curr. Biol. Aug 2007;17:R611-4
Abstract
A new study has shown that, near the tip of a growing axon, dephosphorylation of the microtubule-associated protein Doublecortin is controlled by protein phosphatase 1 and its regulator spinophilin. This results in spatially regulated microtubule bundling within the axon and more efficient axon outgrowth.
Mesh Headings (Keywords): Animals, Mice, Microtubule-Associated Proteins, Microtubules, Neurites, Neuropeptides, Phosphorylation
Check for Full Text / PubMed Unique Identifier (PMID): 17686437
This abstract is part of PubMed, a service of the U.S. National Library of Medicine. PubMed includes more than 17 million citations from MEDLINE and other life science journals for biomedical articles. See Copyright and Disclaimers.
Linked medical terms appearing on this page are added by Healia to help readers find more information and are not part of the original PubMed document.
The data herein was last updated on July 8th, 2008 and may not reflect the most current and accurate data available from NLM.