Autoantibodies in Autism Spectrum Disorders (Asd).
From: Division of Rheumatology, Allergy and Clinical Immunology, UC Davis, Davis, CA 95616, USA.
Annals of the New York Academy of Sciences
- Publish Date: Jun 2007
- ISSN: 0077-8923
- Volume: 1107
- Issue:
- Pages: 79-91
- Medium: Print
- Language: English
- Citation (JAMA): Wills Sharifia, Cabanlit Maricel, Bennett Jeff, et al. Autoantibodies in Autism Spectrum Disorders (Asd).. Ann. N. Y. Acad. Sci. Jun 2007;1107:79-91
Abstract
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders defined behaviorally by abnormalities in social, verbal, and nonverbal communication. The etiologies of ASD are unknown, likely to be the result of a variety of numerous genetic, neurological, environmental, and immunological interactions that lead to a general behavioral phenotype defined as ASD. This review will focus on the various immune system anomalies, in particular, autoantibodies, which have been reported in subjects with ASD. In addition, we will discuss recent studies performed by our group concerning the presence of autoantibodies directed against neural antigens, which are observed in patients with ASD.
Mesh Headings (Keywords): Animals, Autistic Disorder, Autoantibodies, Cell Communication, Humans, Immune System, Neurons
Check for Full Text / PubMed Unique Identifier (PMID): 17804535
This abstract is part of PubMed, a service of the U.S. National Library of Medicine. PubMed includes more than 17 million citations from MEDLINE and other life science journals for biomedical articles. See Copyright and Disclaimers.
Linked medical terms appearing on this page are added by Healia to help readers find more information and are not part of the original PubMed document.
The data herein was last updated on July 8th, 2008 and may not reflect the most current and accurate data available from NLM.