Immunologic Relationship Between Breast Carcinoma and Benign Breast Disease As Detected by the Leukocyte Migration Inhibition Assay.
Journal of the National Cancer Institute
- Publish Date: Nov 1978
- ISSN: 0027-8874
- Volume: 61
- Issue: 5
- Pages: 1181-6
- Medium: Print
- Language: English
- Citation (JAMA): Cannon G B, McCoy J L, Jerome L J, et al. Immunologic Relationship Between Breast Carcinoma and Benign Breast Disease As Detected by the Leukocyte Migration Inhibition Assay.. J. Natl. Cancer Inst. Nov 1978;61:1181-6
Abstract
Patients with benign diseases of the breast reacted in a migration inhibition assay with extracts of breast cancer and benign breast lesions and a human breast cancer-derived cell line, MCF-7. The incidence of reactivity of the patients with benign breast diseases against these antigens was similar to that of breast cancer patients. In addition, patients with breast cancer reacted to some extracts of benign breast lesions. The reactivity occurred in patients with several different histopathologic types of breast lesions, but was not found in women with no detectable pathologic lesions.
Mesh Headings (Keywords): Adenofibroma, Antigens, Neoplasm, Breast Diseases, Breast Neoplasms, Cell Line, Cell Migration Inhibition, Female, Humans, Immunity, Cellular, Leukocytes, Male, Neoplasms, Experimental
Check for Full Text / PubMed Unique Identifier (PMID): 280705
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