The Fast Acetylator Phenotype in Diabetes Mellitus: Abnormal Prevalence and Association with the Abo Blood Groups.
Diabetologia
- Publish Date: Aug 1984
- ISSN: 0012-186X
- Volume: 27
- Issue: 2
- Pages: 235-7
- Medium: Print
- Language: English
- Citation (JAMA): Pontiroli A E, Mosca A, de Pasqua A, et al. The Fast Acetylator Phenotype in Diabetes Mellitus: Abnormal Prevalence and Association with the Abo Blood Groups.. Diabetologia Aug 1984;27:235-7
Abstract
The acetylator phenotype and ABO blood groups were evaluated in 55 normal subjects and in 156 diabetic patients [61 with Type 1 (insulin-dependent) diabetes and 95 with Type 2 (non-insulin-dependent) diabetes]. The prevalence of fast acetylators was significantly higher in the Type 1 diabetic patients (53%) than in the control subjects (29%). In the Type 2 diabetic patients the prevalence was 39%, and thus not significantly different from the control or Type 1 diabetic groups. In the Type 2 diabetic patients, but not in the control or in the Type 1 diabetic subjects, an association between the fast acetylator phenotype and the B blood group was found.
Mesh Headings (Keywords): ABO Blood-Group System, Acetylation, Adolescent, Adult, Aged, Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Female, Hemoglobin A, Glycosylated, Humans, Male, Middle Aged, Phenotype
Check for Full Text / PubMed Unique Identifier (PMID): 6489656
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