Topic: Humans

Journal: The Journal of Biological Chemistry

Documents

A list of abstracts that contain a topic of "Humans" and a journal name of "The Journal of Biological Chemistry".

• Studies on the Transcriptional Regulation of Cholesterol 24-hydroxylase (Cyp46a1): Marked Insensitivity Toward Different Regulatory Axes.

  PMID: 16321981

• Phosphorylation of Human Ctp Synthetase 1 by Protein Kinase A: Identification of Thr455 As a Major Site of Phosphorylation.

  PMID: 17189248

• Identification of Epi64 As a Gtpase-activating Protein Specific for Rab27a.

  PMID: 16923811

• Electron Paramagnetic Resonance Spectroscopy of Site-directed Spin Labels Reveals the Structural Heterogeneity in the N-terminal Domain of Apoa-i in Solution.

  PMID: 17204472

• Requirement of the Protein B23 for Nucleolar Disassembly Induced by the Frgy2a Family Proteins.

  PMID: 16415342

• The Role of the Phospho-cdk2/Cyclin A Recruitment Site in Substrate Recognition.

  PMID: 16707497

• Semaphorin-3a and Semaphorin-3f Work Together to Repel Endothelial Cells and to Inhibit Their Survival by Induction of Apoptosis.

  PMID: 17569671

• The Stability and Anti-apoptotic Function of A1 Are Controlled by Its C Terminus.

  PMID: 16551634

• The Lysine-specific Demethylase 1 is Required for Cell Proliferation in Both P53-dependent and -independent Manners.

  PMID: 17409384

• A Specific Isoform of Nonmuscle Myosin Ii-c is Required for Cytokinesis in a Tumor Cell Line.

  PMID: 16790446

• Phosphorylation of Thyroid Hormone Receptor-associated Nuclear Receptor Corepressor Holocomplex by the Dna-dependent Protein Kinase Enhances Its Histone Deacetylase Activity.

  PMID: 17242407

• Fusion Peptide of Influenza Hemagglutinin Requires a Fixed Angle Boomerang Structure for Activity.

  PMID: 16407195

• Local Unfolding in a Destabilized, Pathogenic Variant of Superoxide Dismutase 1 Observed with H/D Exchange and Mass Spectrometry.

  PMID: 16644738

• Temperature-sensitive Eif5a Mutant Accumulates Transcripts Targeted to the Nonsense-mediated Decay Pathway.

  PMID: 16987817

• The Plasma Membrane Ca2+ Pump Isoform 4a Differs from Isoform 4b in the Mechanism of Calmodulin Binding and Activation Kinetics: Implications for Ca2+ Signaling.

  PMID: 17595168

• The Role of Properdin in the Assembly of the Alternative Pathway C3 Convertases of Complement.

  PMID: 16301317

• Vaccinia Virus Uracil Dna Glycosylase Interacts with the A20 Protein to Form a Heterodimeric Processivity Factor for the Viral Dna Polymerase.

  PMID: 16326701

• Pat1a Modulates Intracellular Transport and Processing of Amyloid Precursor Protein (App), Aplp1, and Aplp2.

  PMID: 17050537

• Ganglioside Gd1a is an Essential Coreceptor for Toll-like Receptor 2 Signaling in Response to the B Subunit of Type Iib Enterotoxin.

  PMID: 17227759

• New Insights into Bs69 Functions.

  PMID: 16565076

• Assembly of a Polymeric Chain of Sumo1 on Human Topoisomerase I in Vitro.

  PMID: 16428803

• Design of a Long Acting Peptide Functioning As Both a Glucagon-like Peptide-1 Receptor Agonist and a Glucagon Receptor Antagonist.

  PMID: 16505481

• Estrogen-occupied Estrogen Receptor Represses Cyclin G2 Gene Expression and Recruits a Repressor Complex at the Cyclin G2 Promoter.

  PMID: 16608856

• Disruption of a Tight Cluster Surrounding Tyrosine 131 in the Native Conformation of Antithrombin Iii Activates It for Factor Xa Inhibition.

  PMID: 16940049

• Crystal Structure of Aminopeptidase N (Proteobacteria Alanyl Aminopeptidase) from Escherichia Coli and Conformational Change of Methionine 260 Involved in Substrate Recognition.

  PMID: 16885166

• Dyrk1a Phosphorylates Alpha-synuclein and Enhances Intracellular Inclusion Formation.

  PMID: 16959772

• A Comprehensive Structure-function Map of the Intracellular Surface of the Human C5a Receptor. Ii. Elucidation of G Protein Specificity Determinants.

  PMID: 17090530

• The 19 S Proteasomal Subunit Poh1 Contributes to the Regulation of C-jun Ubiquitination, Stability, and Subcellular Localization.

  PMID: 16569633

• The Structural and Functional Units of Heteromeric Amino Acid Transporters. The Heavy Subunit Rbat Dictates Oligomerization of the Heteromeric Amino Acid Transporters.

  PMID: 16825196

• The Cytoplasmic Substrate Permeation Pathway of Serotonin Transporter.

  PMID: 17008313

• Traffic to the Malaria Parasite Food Vacuole: a Novel Pathway Involving a Phosphatidylinositol 3-phosphate-binding Protein.

  PMID: 17289673

• The Existence of Multiple Conformers of Interleukin-21 Directs Engineering of a Superpotent Analogue.

  PMID: 17565991

• In Vitro Fluorescence Anisotropy Analysis of the Interaction of Full-length Src1a with Estrogen Receptors Alpha and Beta Supports an Active Displacement Model for Coregulator Utilization.

  PMID: 17135255

• The P174l Mutation in Human Sco1 Severely Compromises Cox17-dependent Metallation but Does Not Impair Copper Binding.

  PMID: 16520371

• Structure of Human Spindlin1. Tandem Tudor-like Domains for Cell Cycle Regulation.

  PMID: 17082182

• Crystal Structure of Human Estrogen-related Receptor Alpha in Complex with a Synthetic Inverse Agonist Reveals Its Novel Molecular Mechanism.

  PMID: 17556356

• Functional Human Mitochondrial Dna Polymerase Gamma Forms a Heterotrimer.

  PMID: 16263719

• Sensing of Lysophospholipids by Trpc5 Calcium Channel.

  PMID: 16368680

• Calcyon, a Novel Partner of Clathrin Light Chain, Stimulates Clathrin-mediated Endocytosis.

  PMID: 16595675

• The Rac Binding Domain/Irsp53-mim Homology Domain of Irsp53 Induces Rac-dependent Membrane Deformation.

  PMID: 17003044

• Gamma-secretase-mediated Release of the Low Density Lipoprotein Receptor-related Protein 1b Intracellular Domain Suppresses Anchorage-independent Growth of Neuroglioma Cells.

  PMID: 17227771

• Transcriptional Repression by a Conserved Intronic Sequence in the Nicotinic Receptor Alpha3 Subunit Gene.

  PMID: 17504758

• The Different Intermolecular Interactions of the Soluble Copper-binding Domains of the Menkes Protein, Atp7a.

  PMID: 17545667

• Structural Basis for the Function of Dcn-1 in Protein Neddylation.

  PMID: 17597076

• Feedback Inhibition of Pantothenate Kinase Regulates Pantothenol Uptake by the Malaria Parasite.

  PMID: 17581817

• Luminal Chloride-dependent Activation of Endosome Calcium Channels: Patch Clamp Study of Enlarged Endosomes.

  PMID: 17609211

• Real Time Single Cell Analysis of Bid Cleavage and Bid Translocation During Caspase-dependent and Neuronal Caspase-independent Apoptosis.

  PMID: 16407197

• Human Dna Polymerase N (Poln) is a Low Fidelity Enzyme Capable of Error-free Bypass of 5s-thymine Glycol.

  PMID: 16787914

• The Putative Chloride Channel Hclca2 Has a Single C-terminal Transmembrane Segment.

  PMID: 16873362

• Multiple Antigenic Mimotopes of Hiv Carbohydrate Antigens: Relating Structure and Antigenicity.

  PMID: 16899462

• Mechanisms by Which Bloom Protein Can Disrupt Recombination Intermediates of Okazaki Fragment Maturation.

  PMID: 16950766

• Cyclophilin a Protects Peg3 from Hypermethylation and Inactive Histone Modification.

  PMID: 17071620

• Post-transcriptional Regulation of Rnase-l Expression is Mediated by the 3'-untranslated Region of Its Mrna.

  PMID: 17237228

• Identification of a Glycosaminoglycan Binding Region of the Alpha C Protein That Mediates Entry of Group B Streptococci into Host Cells.

  PMID: 17259175

• Tryptophan 32 Potentiates Aggregation and Cytotoxicity of a Copper/Zinc Superoxide Dismutase Mutant Associated with Familial Amyotrophic Lateral Sclerosis.

  PMID: 17389599

• Structure-function Relationships of the Viral Rna-dependent Rna Polymerase: Fidelity, Replication Speed, and Initiation Mechanism Determined by a Residue in the Ribose-binding Pocket.

  PMID: 17400557

• Myosin Vb is Required for Trafficking of the Cystic Fibrosis Transmembrane Conductance Regulator in Rab11a-specific Apical Recycling Endosomes in Polarized Human Airway Epithelial Cells.

  PMID: 17462998

• 11beta-hydroxysteroid Dehydrogenase Type 1 Regulation by Intracellular Glucose 6-phosphate Provides Evidence for a Novel Link Between Glucose Metabolism and Hypothalamo-pituitary-adrenal Axis Function.

  PMID: 17588937

• Structural Regions of Md-2 That Determine the Agonist-antagonist Activity of Lipid Iva.

  PMID: 16407172

• Ets-1-dependent Expression of Vascular Endothelial Growth Factor Receptors is Activated by Latency-associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus Through Interaction with Daxx.

  PMID: 16861237

• Neuroglycan C is a Novel Midkine Receptor Involved in Process Elongation of Oligodendroglial Precursor-like Cells.

  PMID: 16901907

• Orexin-1 Receptor-cannabinoid Cb1 Receptor Heterodimerization Results in Both Ligand-dependent and -independent Coordinated Alterations of Receptor Localization and Function.

  PMID: 17015451

• A Novel Corepressor, Bcor-l1, Represses Transcription Through an Interaction with Ctbp.

  PMID: 17379597

• The Human Angiotensin Ii Type 1 Receptor +1166 A/C Polymorphism Attenuates Microrna-155 Binding.

  PMID: 17588946

• P53 is Cleaved by Caspases Generating Fragments Localizing to Mitochondria.

  PMID: 16531411

• The Nicastrin-like Protein Nicalin Regulates Assembly and Stability of the Nicalin-nodal Modulator (Nomo) Membrane Protein Complex.

  PMID: 17261586

• Intranuclear Protein Transduction Through a Nucleoside Salvage Pathway.

  PMID: 17525162

• Ligands for the Beta-glucan Receptor, Dectin-1, Assigned Using "Designer" Microarrays of Oligosaccharide Probes (Neoglycolipids) Generated from Glucan Polysaccharides.

  PMID: 16371356

• Recognition and Blocking of Hiv-1 Gp41 Pre-transmembrane Sequence by Monoclonal 4e10 Antibody in a Raft-like Membrane Environment.

  PMID: 17050535

• Rapid Kinetics of Na+ Binding to Thrombin.

  PMID: 17074754

• Complete Restoration of Cell Surface Activity of Transmembrane-truncated Mt1-mmp by a Glycosylphosphatidylinositol Anchor. Implications for Mt1-mmp-mediated Prommp2 Activation and Collagenolysis in Three-dimensions.

  PMID: 17158888

• Trpa1 is Differentially Modulated by the Amphipathic Molecules Trinitrophenol and Chlorpromazine.

  PMID: 17218316

• Molecular Mechanism of Action of Monocyclam Versus Bicyclam Non-peptide Antagonists in the Cxcr4 Chemokine Receptor.

  PMID: 17599916

• Foxo1 Represses Peroxisome Proliferator-activated Receptor-gamma1 and -gamma2 Gene Promoters in Primary Adipocytes. A Novel Paradigm to Increase Insulin Sensitivity.

  PMID: 16670091

• Prostaglandin E2 Stimulates P53 Transactivational Activity Through Specific Serine 15 Phosphorylation in Human Synovial Fibroblasts. Role in Suppression of C/Ebp/Nf-kappab-mediated Mekk1-induced Mmp-1 Expression.

  PMID: 16714289

• Dissecting the N-terminal Myosin Binding Site of Human Cardiac Myosin-binding Protein C. Structure and Myosin Binding of Domain C2.

  PMID: 17192269

• Hsnm1b is a Novel Telomere-associated Protein.

  PMID: 16606622

• The Mitochondrial Tom Complex is Required for Tbid/Bax-induced Cytochrome C Release.

  PMID: 17635912

• Endotoxin (Lipopolysaccharide) Neutralization by Innate Immunity Host-defense Peptides. Peptide Properties and Plausible Modes of Action.

  PMID: 16293630

• Chaperoning Checkpoint Kinase 1 (Chk1), an Hsp90 Client, with Purified Chaperones.

  PMID: 16330544

• Signal-dependent Control of Gluconeogenic Key Enzyme Genes Through Coactivator-associated Arginine Methyltransferase 1.

  PMID: 16330542

• Naturally Occurring Mutations in Human Mitochondrial Pre-trnaser(Ucn) Can Affect the Transfer Ribonuclease Z Cleavage Site, Processing Kinetics, and Substrate Secondary Structure.

  PMID: 16361254

• Molecular Cloning and Characterization of Udp-glucose Dehydrogenase from the Amphibian Xenopus Laevis and Its Involvement in Hyaluronan Synthesis.

  PMID: 16418163

• Specific Recognition of Apoptotic Cells Reveals a Ubiquitous and Unconventional Innate Immunity.

  PMID: 16707494

• Bok, Bcl-2-related Ovarian Killer, Is Cell Cycle-regulated and Sensitizes to Stress-induced Apoptosis.

  PMID: 16772296

• Mitogen-activated Protein Kinase Kinase-4 Promotes Cell Survival by Decreasing Pten Expression Through an Nf Kappa B-dependent Pathway.

  PMID: 17158870

• Heparin Binding Induces a Conformational Change in Pigment Epithelium-derived Factor.

  PMID: 17202143

• Elmod2 is an Arl2 Gtpase-activating Protein That Also Acts on Arfs.

  PMID: 17452337

• Lysophosphatidic Acid Regulates Trafficking of Beta2-adrenergic Receptors: the Galpha13/P115rhogef/Jnk Pathway Stimulates Receptor Internalization.

  PMID: 17493936

• The Contribution of Conformational Adjustments and Long-range Electrostatic Forces to the Cd2/Cd58 Interaction.

  PMID: 17344209

• Familial Parkinson Mutant Alpha-synuclein Causes Dopamine Neuron Dysfunction in Transgenic Caenorhabditis Elegans.

  PMID: 16260788

• Rna Polymerase Ii Blockage by Cisplatin-damaged Dna. Stability and Polyubiquitylation of Stalled Polymerase.

  PMID: 16275646

• Herc5, an Interferon-induced Hect E3 Enzyme, is Required for Conjugation of Isg15 in Human Cells.

  PMID: 16407192

• Hiv-1 Gp120-mediated Apoptosis of T Cells is Regulated by the Membrane Tyrosine Phosphatase Cd45.

  PMID: 16524887

• Expression of a Functional Drosophila Melanogaster Cmp-sialic Acid Synthetase. Differential Localization of the Drosophila and Human Enzymes.

  PMID: 16537535

• Metalloprotease Inhibitors Gm6001 and Tapi-0 Inhibit the Obligate Intracellular Human Pathogen Chlamydia Trachomatis by Targeting Peptide Deformylase of the Bacterium.

  PMID: 16565079

• A Zinc-binding Region in Vif Binds Cul5 and Determines Cullin Selection.

  PMID: 16636053

• A Structural Determinant of Human Cytomegalovirus Us2 Dictates the Down-regulation of Class I Major Histocompatibility Molecules.

  PMID: 16687410

• C-jun N-terminal Kinase is Necessary for Platelet-derived Growth Factor-mediated Chemotaxis in Primary Fibroblasts.

  PMID: 16760468

• Cd8alphabeta Has Two Distinct Binding Modes of Interaction with Peptide-major Histocompatibility Complex Class I.

  PMID: 16840780

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