Topic: Rats
Journal: Journal of Medicinal Chemistry
Documents
A list of abstracts that contain a topic of "Rats" and a journal name of "Journal of Medicinal Chemistry".
Discovery and Characterization of 4'-(2-furyl)-n-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (Las38096), a Potent, Selective, and Efficacious A2b Adenosine Receptor Antagonist.
PMID: 17469811
Synthesis and Structure-activity Relationship of Small-molecule Malonyl Coenzyme A Decarboxylase Inhibitors.
PMID: 16509570
Dihydropyridopyrazinones and Dihydropteridinones As Corticotropin-releasing Factor-1 Receptor Antagonists: Structure-activity Relationships and Computational Modeling.
PMID: 17402721
3-[5-(4,5-dihydro-1h-imidazol-2-yl)-furan-2-yl]phenylamine (Amifuraline), a Promising Reversible and Selective Peripheral Mao-a Inhibitor.
PMID: 16942031
Discovery and Structure-activity Relationships of Piperidinone- and Piperidine-constrained Phenethylamines As Novel, Potent, and Selective Dipeptidyl Peptidase Iv Inhibitors.
PMID: 17367123
Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun Nh2-terminal Kinase Inhibitors.
PMID: 16854050
Low-calcemic, Highly Antiproliferative, 1-difluoromethyl Hybrid Analogs of the Natural Hormone 1alpha,25-dihydroxyvitamin D3: Design, Synthesis, and Preliminary Biological Evaluation.
PMID: 17149880
4,5-dihydroxypyrimidine Carboxamides and N-alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective Hiv Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species.
PMID: 17154493
Branched Diacylglycerol-lactones As Potent Protein Kinase C Ligands and Alpha-secretase Activators.
PMID: 16539391
Identification of a Nonpeptidic and Conformationally Restricted Bradykinin B1 Receptor Antagonist with Anti-inflammatory Activity.
PMID: 17243660
Novel Series of Potent, Nonsteroidal, Selective Androgen Receptor Modulators Based on 7h-[1,4]oxazino[3,2-g]quinolin-7-ones.
PMID: 17439112
6-(4-chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3h)-one-based Melanin-concentrating Hormone Receptor 1 Antagonist.
PMID: 17125263
Pyrrolopyridine Inhibitors of Mitogen-activated Protein Kinase-activated Protein Kinase 2 (Mk-2).
PMID: 17480064
Exploring the Structure-activity Relationship of the Ethylamine Portion of 3-iodothyronamine for Rat and Mouse Trace Amine-associated Receptor 1.
PMID: 17497842
Radiolabeled Phenethylguanidines: Novel Imaging Agents for Cardiac Sympathetic Neurons and Adrenergic Tumors.
PMID: 17419605
Fine-tuning the Amphiphilicity: a Crucial Parameter in the Design of Potent Alpha-phenyl-n-tert-butylnitrone Analogues.
PMID: 17649989
Three-dimensional Quantitative Structure-activity Relationships of Atp-sensitive Potassium (Katp) Channel Openers Belonging to the 3-alkylamino-4h-1,2,4-benzo- and 3-alkylamino-4h-1,2,4-pyridothiadiazine 1,1-dioxide Families.
PMID: 17154508
Anthranilic Acid Based Cck1 Receptor Antagonists and Cck-8 Have a Common Step in Their "Receptor Desmodynamic Processes".
PMID: 16610788
Impact of the 3,6,9-trioxadecyloxy Group on Desazadesferrithiocin Analogue Iron Clearance and Organ Distribution.
PMID: 17564424
Synthesis and Simple 18f-labeling of 3-fluoro-5-(2-(2-(Fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile As a High Affinity Radioligand for Imaging Monkey Brain Metabotropic Glutamate Subtype-5 Receptors with Positron Emission Tomography.
PMID: 17571866
Structure Activity Relationships of 5-, 6-, and 7-methyl-substituted Azepan-3-one Cathepsin K Inhibitors.
PMID: 16509577
Fatty Acid Amide Hydrolase Inhibitors from Virtual Screening of the Endocannabinoid System.
PMID: 16854070
Synthesis and Evaluation of Isomeric (17alpha,20e)-11beta-methoxy-21-(Trifluoromethylphenyl)-19-norpregna-1,3,5(10),20-tetraene-3,17beta-diols As Eralpha-hormone Binding Domain Ligands: Effect of the Methoxy Group on Receptor Binding and Uterotrophic Growth.
PMID: 17266199